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Aging
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Core Pathways of Aging
johnswentworth
28 Mar 2021 0:31 UTC
266
points
126
comments
22
min read
LW
link
1
review
Anti-Aging: State of the Art
JackH
31 Dec 2020 19:07 UTC
374
points
176
comments
11
min read
LW
link
1
review
Aging and the geroscience hypothesis
DirectedEvolution
12 Jul 2023 7:16 UTC
54
points
14
comments
5
min read
LW
link
Thoughts on being mortal
Joe Carlsmith
1 Jan 2021 19:17 UTC
83
points
5
comments
6
min read
LW
link
Why SENS makes sense
emanuele ascani
22 Feb 2020 16:28 UTC
28
points
2
comments
31
min read
LW
link
[Question]
Why is loss of muscle cells not considered one of the hallmarks of aging?
ChristianKl
5 Jan 2021 14:19 UTC
11
points
9
comments
1
min read
LW
link
Highlights of Comparative and Evolutionary Aging
johnswentworth
22 May 2020 17:01 UTC
56
points
10
comments
2
min read
LW
link
Project Proposal: Gears of Aging
johnswentworth
9 May 2020 18:47 UTC
58
points
43
comments
7
min read
LW
link
Bryan Johnson and a search for healthy longevity
NancyLebovitz
27 Jul 2024 15:28 UTC
18
points
17
comments
1
min read
LW
link
Homeostasis and “Root Causes” in Aging
johnswentworth
5 Jan 2020 18:43 UTC
86
points
25
comments
3
min read
LW
link
The Lens, Progerias and Polycausality
johnswentworth
8 Mar 2020 17:53 UTC
71
points
8
comments
3
min read
LW
link
Hypothesis: lab mice have more active transposons then wild mice
ChristianKl
5 Jun 2021 12:36 UTC
19
points
14
comments
1
min read
LW
link
Should we vaccinate against PGBD5 which codes for a transposase?
ChristianKl
8 Jun 2021 19:22 UTC
18
points
5
comments
1
min read
LW
link
Adaptive Immune System Aging
johnswentworth
13 Mar 2020 3:47 UTC
75
points
9
comments
3
min read
LW
link
Addendum to “Amyloid Plaques: Medical Goodhart, Chemical Streetlight”
J Bostock
2 Sep 2021 17:42 UTC
10
points
1
comment
2
min read
LW
link
How much should we value life?
Adam Zerner
6 Sep 2021 22:30 UTC
30
points
25
comments
38
min read
LW
link
[Question]
Does anyone have an anki deck on ageing / rejuvenation biotechnology that they could share?
freedomandutility
10 Oct 2021 16:54 UTC
1
point
0
comments
1
min read
LW
link
Nightclubs in Heaven?
J Bostock
5 Nov 2021 23:28 UTC
10
points
3
comments
2
min read
LW
link
[Preprint for commenting] Fighting Aging as an Effective Altruism Cause
avturchin
16 Apr 2018 13:55 UTC
9
points
5
comments
1
min read
LW
link
Second-order selection against the immortal
Malmesbury
3 Dec 2021 5:01 UTC
45
points
47
comments
6
min read
LW
link
Internet Literacy Atrophy
Elizabeth
26 Dec 2021 12:30 UTC
111
points
49
comments
3
min read
LW
link
(acesounderglass.com)
Immortality: A Practical Guide
G0W51
26 Jan 2015 16:17 UTC
53
points
62
comments
36
min read
LW
link
If you want to live longer, become President
Bezzi
11 Feb 2022 23:14 UTC
8
points
11
comments
7
min read
LW
link
Wormy the Worm
River Lewis
21 May 2022 15:34 UTC
3
points
23
comments
5
min read
LW
link
(heytraveler.substack.com)
Age changes what you care about
Dentin
16 Oct 2022 15:36 UTC
141
points
37
comments
2
min read
LW
link
SENS and Givewell: Conversation between Holden Karnofsky and Aubrey de Grey
curiousepic
5 Mar 2013 19:24 UTC
30
points
12
comments
12
min read
LW
link
Living Forever is Hard, part 2: Adult Longevity
gwern
9 Sep 2011 18:52 UTC
20
points
11
comments
2
min read
LW
link
Prediction market: Will John Wentworth’s Gears of Aging series hold up in 2033?
tailcalled
25 Feb 2023 20:15 UTC
15
points
4
comments
1
min read
LW
link
(manifold.markets)
Why We Age, Part 2: Non-adaptive theories
willbradshaw
26 May 2020 17:41 UTC
89
points
22
comments
11
min read
LW
link
(apomorphic.com)
Why We Age, Part 1: What ageing is and is not
willbradshaw
24 May 2020 9:06 UTC
55
points
5
comments
7
min read
LW
link
(apomorphic.com)
Compression of morbidity
DirectedEvolution
12 Jul 2023 15:26 UTC
12
points
0
comments
3
min read
LW
link
Cryonics and Regret
MvB
24 Jul 2023 9:16 UTC
187
points
34
comments
2
min read
LW
link
The Fountain of Health: a First Principles Guide to Rejuvenation
PhilJackson
7 Jan 2023 18:34 UTC
115
points
38
comments
41
min read
LW
link
[Question]
Why rationalists are not much concerned about mortality?
SurvivalBias
10 Feb 2022 0:11 UTC
18
points
92
comments
1
min read
LW
link
Here’s Why Indefinite Life Extension Will Never Work, Even Though it Does.
HomingHamster
4 Jun 2024 18:48 UTC
−13
points
5
comments
18
min read
LW
link
Beyond Biomarkers: Understanding Multiscale Causality
Matěj Nekoranec
7 Jul 2024 9:56 UTC
13
points
0
comments
7
min read
LW
link
“The Singularity Is Nearer” by Ray Kurzweil—Review
Lavender
8 Jul 2024 21:32 UTC
22
points
0
comments
4
min read
LW
link
Wrinkles
johnswentworth
19 Nov 2019 22:59 UTC
81
points
14
comments
4
min read
LW
link
Living Forever is Hard, or, The Gompertz Curve
gwern
17 May 2011 21:08 UTC
67
points
87
comments
3
min read
LW
link
Longevity interventions when young
George3d6
24 Jul 2020 11:25 UTC
45
points
17
comments
39
min read
LW
link
(cerebralab.com)
Introducing the Longevity Research Institute
sarahconstantin
8 May 2018 3:30 UTC
54
points
20
comments
1
min read
LW
link
(srconstantin.wordpress.com)
Introducing the Longevity Research Institute
sarahconstantin
14 Dec 2018 20:20 UTC
79
points
11
comments
1
min read
LW
link
(srconstantin.wordpress.com)
Lifeism in the midst of death
TobyBartels
9 Dec 2012 13:28 UTC
97
points
19
comments
4
min read
LW
link
Does Age Bring Wisdom?
Scott Alexander
8 Nov 2017 7:20 UTC
37
points
8
comments
4
min read
LW
link
(slatestarcodex.com)
Why people want to die
PhilGoetz
24 Aug 2015 20:13 UTC
93
points
174
comments
2
min read
LW
link
Are healthy choices effective for improving live expectancy anymore?
Christopher King
8 May 2023 21:25 UTC
6
points
4
comments
1
min read
LW
link
Human performance, psychometry, and baseball statistics
Craig_Heldreth
15 Oct 2010 13:13 UTC
33
points
21
comments
6
min read
LW
link
Naked mole-rats: A case study in biological weirdness
eukaryote
19 May 2019 18:40 UTC
95
points
14
comments
3
min read
LW
link
(eukaryotewritesblog.com)
An alarming fact about the anti-aging community
diegocaleiro
16 Feb 2015 17:49 UTC
44
points
65
comments
2
min read
LW
link
[LINK] Larry = Harry sans magic? Google vs. Death
Shmi
18 Sep 2013 16:49 UTC
36
points
55
comments
1
min read
LW
link
Do not miss the cutoff for immortality! There is a probability that you will live forever as an immortal superintelligent being and you can increase your odds by convincing others to make achieving the technological singularity as quickly and safely as possible the collective goal/project of all of humanity, Similar to “Fable of the Dragon-Tyrant.”
Oliver--Klozoff
29 Jun 2023 3:45 UTC
1
point
0
comments
28
min read
LW
link
[Question]
What to make of Aubrey de Grey’s prediction?
Rafael Harth
28 Feb 2020 19:25 UTC
23
points
18
comments
1
min read
LW
link
BHTV: de Grey and Yudkowsky
Eliezer Yudkowsky
13 Dec 2008 15:28 UTC
10
points
12
comments
1
min read
LW
link
Book review: Age Later
PeterMcCluskey
27 Oct 2020 4:21 UTC
28
points
3
comments
4
min read
LW
link
(www.bayesianinvestor.com)
Impact of aging research besides LEV
emanuele ascani
6 Jun 2019 10:42 UTC
15
points
0
comments
7
min read
LW
link
Three Open Problems in Aging
johnswentworth
7 Nov 2020 19:39 UTC
48
points
8
comments
5
min read
LW
link
If calorie restriction works in humans, should we have observed it already?
Mark_Eichenlaub
24 Apr 2012 4:28 UTC
32
points
33
comments
1
min read
LW
link
Aging: A Surprisingly Tractable Problem
Quinn
8 Apr 2021 19:25 UTC
11
points
0
comments
1
min read
LW
link
[linkpost] Project Blueprint: ‘Measuring and then maximally reversing the quantified biological age of my organs’
matteodimaio
16 Nov 2021 2:48 UTC
2
points
0
comments
1
min read
LW
link
Aldix and the Book of Life
ville
1 Jan 2024 17:23 UTC
1
point
0
comments
4
min read
LW
link
(medium.com)
Being a donor for Fecal Microbiota Transplants (FMT): Do good & earn easy money (up to 180k/y)
EternallyBlissful
8 Jul 2022 6:17 UTC
36
points
26
comments
8
min read
LW
link
(forum.effectivealtruism.org)
(DIY) FMT for Anti-Aging & Biohacking
EternallyBlissful
28 Nov 2022 15:49 UTC
26
points
7
comments
6
min read
LW
link
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