Biosecurity

TagLast edit: 2 Apr 2022 19:06 UTC by Raemon

Trialing Far UVC and Glycol Vapors at BIDA

jefftk15 Aug 2025 2:20 UTC

19 points

1 comment2 min readLW link

(www.jefftk.com)

The Offense-Defense Balance of Gene Drives

Maxwell Tabarrok27 Sep 2024 16:47 UTC

23 points

1 comment4 min readLW link

(www.maximum-progress.com)

How Much Data From a Sequencing Run?

jefftk26 Jun 2025 2:30 UTC

13 points

0 comments2 min readLW link

(www.jefftk.com)

The AI Revolution in Biology

Roman Leventov26 May 2024 9:30 UTC

13 points

0 comments1 min readLW link

(www.cognitiverevolution.ai)

Scaling the NAO’s Stealth Pathogen Early-Warning System

jefftk2 Apr 2025 13:28 UTC

12 points

0 comments2 min readLW link

(naobservatory.org)

Detection of Asymptomatically Spreading Pathogens

jefftk5 Dec 2024 18:20 UTC

45 points

10 comments7 min readLW link

(www.jefftk.com)

Out-of-distribution Bioattacks

jefftk2 Dec 2023 12:20 UTC

66 points

15 comments2 min readLW link

(www.jefftk.com)

[Question] How has the total amount of gain-of-function research worldwide grown/shrunk over time?

johnswentworth19 May 2022 15:57 UTC

29 points

7 comments1 min readLW link

Defending against hypothetical moon life during Apollo 11

eukaryote7 Jan 2024 4:49 UTC

58 points

9 comments32 min readLW link

(eukaryotewritesblog.com)

My Mid-Career Transition into Biosecurity

jefftk2 Oct 2023 21:20 UTC

26 points

4 comments2 min readLW link

(www.jefftk.com)

[Question] Why not constrain wetlabs instead of AI?

Lone Pine21 Mar 2023 18:02 UTC

15 points

10 comments1 min readLW link

Biosecurity Culture, Computer Security Culture

jefftk30 Aug 2023 16:40 UTC

103 points

11 comments2 min readLW link

(www.jefftk.com)

Enhancing biosecurity with language models: defining research directions

mic26 Mar 2024 12:30 UTC

12 points

0 comments13 min readLW link

(papers.ssrn.com)

Sequencing Intro

jefftk29 Aug 2022 17:50 UTC

39 points

3 comments5 min readLW link

(www.jefftk.com)

Public Weights?

jefftk2 Nov 2023 2:50 UTC

49 points

19 comments3 min readLW link

(www.jefftk.com)

The Four Pillars: A Hypothesis for Countering Catastrophic Biological Risk

ASB2 Oct 2025 20:20 UTC

9 points

0 comments14 min readLW link

(defensesindepth.bio)

Intercept article about lab accidents

ChristianKl7 Nov 2022 21:10 UTC

23 points

9 comments1 min readLW link

(theintercept.com)

Joseph Bloom on choosing AI Alignment over bio, what many aspiring researchers get wrong, and more (interview)

Ruby and Joseph Bloom

17 Sep 2023 18:45 UTC

27 points

2 comments8 min readLW link

Case Rates to Sequencing Reads

jefftk21 Sep 2022 2:00 UTC

15 points

4 comments4 min readLW link

(www.jefftk.com)

Moderately Skeptical of “Risks of Mirror Biology”

Davidmanheim20 Dec 2024 12:57 UTC

31 points

3 comments9 min readLW link

(substack.com)

Real biosafety is socially inconvenient

ChristianKl2 Apr 2022 18:50 UTC

33 points

15 comments2 min readLW link

[Linkpost] “Intensity and frequency of extreme novel epidemics” by Mariani et al. (2021)

T43128 Sep 2022 3:31 UTC

10 points

0 comments2 min readLW link

(pubmed.ncbi.nlm.nih.gov)

Biological risk from the mirror world

jasoncrawford12 Dec 2024 19:07 UTC

334 points

38 comments7 min readLW link

(newsletter.rootsofprogress.org)

Benchmarking Bowtie2 Threading

jefftk1 Dec 2023 20:20 UTC

9 points

0 comments1 min readLW link

(www.jefftk.com)

Covid 10/20/22: Wait, We Did WHAT?

Zvi20 Oct 2022 21:50 UTC

55 points

16 comments16 min readLW link

(thezvi.wordpress.com)

Far-UVC Light Update: No, LEDs are not around the corner (tweetstorm)

Davidmanheim2 Nov 2022 12:57 UTC

74 points

29 comments4 min readLW link

(twitter.com)

Polio Lab Leak Caught with Wastewater Sampling

Cullen7 Apr 2023 1:06 UTC

82 points

3 comments1 min readLW link

(www.eurosurveillance.org)

Last Line of Defense: Minimum Viable Shelters for Mirror Bacteria

Ulrik Horn21 Dec 2024 8:28 UTC

13 points

26 comments21 min readLW link

Scalable And Transferable Black-Box Jailbreaks For Language Models Via Persona Modulation

Soroush Pour, rusheb, Quentin FEUILLADE--MONTIXI, Arush and scasper

7 Nov 2023 17:59 UTC

38 points

2 comments2 min readLW link

(arxiv.org)

[Retracted] Guess I Was Wrong About AIxBio Risks

J Bostock29 Sep 2025 11:44 UTC

62 points

7 comments5 min readLW link

Biosafety Regulations (BMBL) and their relevance for AI

Štěpán Los29 Jun 2023 19:22 UTC

4 points

0 comments4 min readLW link

RAND report finds no effect of current LLMs on viability of bioterrorism attacks

StellaAthena25 Jan 2024 19:17 UTC

94 points

14 comments1 min readLW link

(www.rand.org)

How to solve the misuse problem assuming that in 10 years the default scenario is that AGI agents are capable of synthetizing pathogens

jeremtti27 Nov 2024 21:17 UTC

6 points

0 comments9 min readLW link

The Universal Lockpick Hypothesis: A Structural Vulnerability of All Life

Cole Holin23 Mar 2025 19:27 UTC

1 point

0 comments2 min readLW link

AI and Chemical, Biological, Radiological, & Nuclear Hazards: A Regulatory Review

Elliot Mckernon and Deric Cheng

10 May 2024 8:41 UTC

7 points

1 comment10 min readLW link

AI as a Civilizational Risk Part 4/6: Bioweapons and Philosophy of Modification

PashaKamyshev1 Nov 2022 20:50 UTC

7 points

1 comment8 min readLW link

A call for a quantitative report card for AI bioterrorism threat models

Juno4 Dec 2023 6:35 UTC

12 points

0 comments10 min readLW link

Enhancing Genomic Foundation Model Robustness through Iterative Black-Box Adversarial Training

Jeyashree Krishnan and Ajay Mandyam Rangarajan

14 Oct 2025 20:54 UTC

4 points

0 comments7 min readLW link

Apply to attend a Global Challenges Project workshop in 2025!

LiamE11 Dec 2024 0:41 UTC

6 points

0 comments2 min readLW link

(forum.effectivealtruism.org)

Weekly Incidence vs Cumulative Infections

jefftk7 Sep 2023 2:30 UTC

13 points

6 comments1 min readLW link

(www.jefftk.com)

More Than Just A, T, C, and G: Screening for Hidden Dangers in DNA Sequences

sgd21 Apr 2025 20:12 UTC

1 point

0 comments11 min readLW link

Mirror Organisms Are Not Immune to Predation

Matt Dellago22 May 2025 11:10 UTC

27 points

5 comments1 min readLW link

The Dangers of Mirrored Life

Niko_McCarty and fin

12 Dec 2024 20:58 UTC

121 points

9 comments29 min readLW link

(www.asimov.press)

Reslab Request for Information: EA hardware projects

Joel Becker26 Oct 2022 21:13 UTC

10 points

0 comments1 min readLW link

[Question] H5N1. Just how bad is the situation?

Q Home8 Jul 2023 22:09 UTC

16 points

8 comments1 min readLW link

Did the Army Poison a Bunch of Women in Minnesota?

rba20 Jun 2025 15:33 UTC

53 points

2 comments4 min readLW link

WHO Biological Risk warning

Jonas Kgomo25 Apr 2023 15:10 UTC

−6 points

2 comments1 min readLW link

Biosecurity and AI: Risks and Opportunities

Steve Newman27 Feb 2024 18:45 UTC

11 points

1 comment7 min readLW link

(www.safe.ai)

Hashmarks: Privacy-Preserving Benchmarks for High-Stakes AI Evaluation

Paul Bricman4 Dec 2023 7:31 UTC

12 points

6 comments16 min readLW link

(arxiv.org)

Why I got the smallpox vaccine in 2023

joec2 Oct 2023 5:11 UTC

25 points

6 comments4 min readLW link

Weekly Incidence Including Delay

jefftk20 Sep 2023 14:00 UTC

11 points

0 comments2 min readLW link

(www.jefftk.com)

Human trials for the Marburg vaccine: funding opportunity?

americanwalrus27 Jul 2022 5:53 UTC

3 points

0 comments1 min readLW link

(www.independent.co.uk)

Do you want a first-principled preparedness guide to prepare yourself and loved ones for potential catastrophes?

Ulrik Horn14 Nov 2023 12:13 UTC

16 points

5 comments15 min readLW link

Day Zero Antivirals for Future Pandemics

Niko_McCarty26 Aug 2024 15:18 UTC

22 points

2 comments10 min readLW link

(www.asimov.press)

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