Thank you for continuing to write these. They’re still my most significant input for how I make day-to-day pandemic-related decisions.
CraigMichael
Colorado is weird
I think most of us are still just happy to get noticed, even with our weed and decriminalized psychedelics. - A Coloradan named Craig
Maybe if they spent the estimated amount of time on the page to read the article (or more), that counts as a view.
You have the most awesome place for these meetups. Looking forward to hanging again!
This is a brilliant policy, thank you for making us aware of it.
Or weight the sources appropriately given the evidence and update when we realize we’ve made a mistake?
Why not spend it on whatever Atomwaffen hates the most?
How did the Kremlin find new agents if signaling loyalty was prohibited?
Not just the wheat, the fertilizer. https://twitter.com/craigtalbert/status/1505813936486199304?s=21
Smoking cigarettes in airplanes made the airplanes safer?
Bear Surprise Freedom Network
I might only add — yes, I see the value in keeping politics off the front page so LW doesn’t become mired in contemporary politics, but it also doesn’t make sense to me that we should pretend to be ignorant of, or act like rationality does not apply to, them. I think there’s something of a middle ground when we’re seeing a trend where banking infrastructure of western nations may be getting ideologically captured that… I mean, it’s more important from a societal dependency level than Eliezer’s example about raising the minimum wage.
I don’t really know how to wrap my head around it yet, but this seems important to emphasize the risk that’s being understated elsewhere.
Update against Peterson, you mean? If so, yes, to an extent.
In a similar way to how I would update against Linus Pauling or Timothy Leary, weighted more towards the later part of their lives (or in Peterson’s case the recent part).
In an older Joe Rogan podcast he said something like “I’ve found a way to monetize SJWs.” Which is maybe the moment that he jumped the shark.
Whereas at one point he organically stumbled on to ideas that he thought were worthwhile but also happened to goad an opposition in to engaging with him and amplifying him, now he’s trying to deliberately engineer narratives that will goad an opposition in to engaging with him and amplifying him.
It’s not that what he’s saying can’t be true anymore, but rather that he (ironically) is optimizing for virality rather than truth… but that’s also basically everyone trying to be an influencer now. So he’s probably not uniquely evil as much as he’s a good person in a lucrative prison of perverse incentives.
In my model, it made sense take precautions to buy time to get vaccines and treatments. We have those now, so the cost-benefit calculation changes. Further wearing a mask is not going to help people avail themselves of them, or encourage institutions to approve existing treatments or accelerate new ones.
I’m grappling with the NNT numbers mentioned above. It’s very much worth it to me to pay $10 for fluvoxamine to say cut the duration of omicron (and perhaps probability of long covid, however small it is) by, say, ~30% (that’s my estimate). It’s even worth it for me at that price to buy enough to not have to watch friends and family suffer longer if they choose to avail themselves.
Peterson’s statement to open Rogan that ‘climate is everything therefore your models are useless’ as a fully general argument against anyone ever knowing anything.
I appreciate you drawing attention to this. It does fall pretty flat the moment you start to think about it. It’s trivially easy to imagine a very poor model of climate and then imagine small tweaks to make it better, and then iteratively improve this overtime. Like we would all imagine and be familiar with. It is a very anti-Bayesian statement from someone who should know better.
I’m also noting no profanity or lude sarcasm. The overall “friendliness” of GPT-3 is surprising, even if it’s glib.
“Friendliness” here meaning like PG-rated answers.
This would be bad news for the tourism industry in Banff. Below was taken on my honeymoon.
Guests of the Banff Springs enjoy royal hospitality as they are served bottled lithium water as they soak in the outdoor pool at Banff Springs. circa 1930s. To boot:
Not only did tourists soak in the spring water, they drank it, too. Bob Elliott, acting operations manager at Banff Upper Hot Springs, said, “Local bars sold bottled hot springs water as a tonic and cure for hangovers. Banff’s mineral water was bottled and sold as ‚Lithia water’ for a short time until the medical experts realized that one of the active ingredients found naturally in the hot springs, Lithium, was addictive. This ended the bottling and consumption, by drinking, of Banff’s mineral springs.”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228356/
Also in the realm of not medical advice: there are perhaps people for who fluvoxamine is safer than paxlovid if they have paxlovid contraindications and could get fluvoxamine instead. I found this article (recently posted elsewhere on Lesswrong) to be worthwhile.
Patients with hypertension, coronary artery disease, atrial fibrillation, and hyperlipidemia should pay close attention to what follows if they are considering starting the drug as they likely will need to stop or modify their cardiac medications and monitor their blood pressure and heart rates closely while taking it.
Paxlovid contains ritonavir-boosted nirmatrelvir.
Ritonavir has long been used to increase the levels of anti-HIV medications by strongly inhibiting the cytochrome P450 (CYP) 3A system which metabolizes many cardiac (and non-cardiac) drugs including nirmatrelvir, the active anti-SARS-CoV2 antiviral.
The EUA for Paxlovid makes it clear how important it is for patients and physicians to be aware of these powerful drug interactions:
Clinicians who are not experienced in prescribing ritonavir-boosted drugs should refer to resources such as the EUA fact sheet for ritonavir-boosted nirmatrelvir (Paxlovid) and the Liverpool COVID-19 Drug Interactions website for additional guidance. Consultation with an expert (e.g., clinical pharmacist, HIV specialist, and/or the patient’s specialist provider[s], if applicable) should also be considered.
Do you currently have thoughts on dosage and duration? IIRC the TOGETHER study was 100mg 2x per day for like 14 days. I’ve seen others recommendation saying 50mg/day is sufficient.
P.S. I won’t take your response as medical advice. Rather, I will interpret only as integers that are fun to type on the Internet.
Is there some place I can see an example?