Do you have an indications that those without the clinical signs of depression (or at least doctor approved state) won’t become acclimated to the drug in a way those that perhaps need it for a balanced state don’t?
I suppose asking a bit differently here, what are the gears here that do the work and how well one might think they they match up with one’s own system that is in place?
Interesting though about using it to improve one’s performance rather than just as an antidepressant or aid to quit smoking. the wiki has some good info but interesting that it doesn’t have a strong effect on dopamine so makes me wonder if looking more at what norepinephrine does, or perhaps the ratio between norepinephrine and dopamine.
Any consideration on the use of other NDRI drugs rather than Bupropion. I’ve not looked into much at this point but Bupropion does have some side effects I would not be too interested in experiencing.
Interesting though about using it to improve one’s performance rather than just as an antidepressant or aid to quit smoking.
IIUC the model here is that “Rat Depression” in fact is just depression (see downthread), so the idea is to use bupropion as just an antidepressant. The hypothesis is that basically-physiologically-ordinary depression displays differently in someone who e.g. already has the skills to notice when their emotions don’t reflect reality, already has the reality-tracking meta-habits which generate CBT-like moves naturally, has relatively weak emotions in general or habitually decouples from their emotions, etc.
I don’t think there’s only one type of depression. Major head trauma does lead to depression in a good portion of people.
It’s my impression Bupropion seems to make it easier to break out of patterns that bind your behavior. That’s true whether that’s smoking (which is why Bupropion is used to help people to stop smoking) or some patterns that contribute to depression.
Bupropion seems to treat akrasia, which is a major part of a lot of “Rat depression”.
Bupoprion is used to help people stop smoking because it is in the same class of molecule as nicotine and triggers many of the same receptors. I wouldn’t expect it to help any other addiction as well as it treats smoking.
Do you have an indications that those without the clinical signs of depression (or at least doctor approved state) won’t become acclimated to the drug in a way those that perhaps need it for a balanced state don’t?
I suppose asking a bit differently here, what are the gears here that do the work and how well one might think they they match up with one’s own system that is in place?
Interesting though about using it to improve one’s performance rather than just as an antidepressant or aid to quit smoking. the wiki has some good info but interesting that it doesn’t have a strong effect on dopamine so makes me wonder if looking more at what norepinephrine does, or perhaps the ratio between norepinephrine and dopamine.
Any consideration on the use of other NDRI drugs rather than Bupropion. I’ve not looked into much at this point but Bupropion does have some side effects I would not be too interested in experiencing.
IIUC the model here is that “Rat Depression” in fact is just depression (see downthread), so the idea is to use bupropion as just an antidepressant. The hypothesis is that basically-physiologically-ordinary depression displays differently in someone who e.g. already has the skills to notice when their emotions don’t reflect reality, already has the reality-tracking meta-habits which generate CBT-like moves naturally, has relatively weak emotions in general or habitually decouples from their emotions, etc.
I don’t think there’s only one type of depression. Major head trauma does lead to depression in a good portion of people.
It’s my impression Bupropion seems to make it easier to break out of patterns that bind your behavior. That’s true whether that’s smoking (which is why Bupropion is used to help people to stop smoking) or some patterns that contribute to depression.
Bupropion seems to treat akrasia, which is a major part of a lot of “Rat depression”.
Bupoprion is used to help people stop smoking because it is in the same class of molecule as nicotine and triggers many of the same receptors. I wouldn’t expect it to help any other addiction as well as it treats smoking.