This sounds like a lot of speculation about the effects of drugs and the like, from what little I know of such things everyone reacts differently so this mostly just tells me about what it feels like for you, not about the effects of estrogen as a whole. I’ve heard wildly different accounts from different trans people.
That said, I often used to wonder if I am trans myself, I don’t really know how to figure that one out though. I’ve had some strong experiences, but every time I’m terrified of exploring them further for fear of what they might mean. Other days I don’t have that compulsion.
I’ve asked lots of trans people but never really got a clear answer, most said they just knew or they felt different, and I...don’t really know. It changes all the time.
The segment on epistemic hyenine is full of a lot of what I would consider “air quotes” for the steps. The increasing knowledge and skepticism could lead to the wrong conclusions especially when you’re using a drug, even a lot of what you say for attention and DMT seems more subjective than anything about the drug.
Also dangerous ideas seems more subjective then anything you could really watch out for. I mean everyone throughout history seems to have a different take on what is dangerous or the deep end.
I think like any drug DMT only gives you what you bring into it, I’ve known some folks who weren’t that different after it. That seems to be the general case for psychedelics. I see what other people have commented but the evidence doesn’t bear that out, and in my experience being in an altered state doesn’t really lead to things you’d miss.
It’s also ironic this is being posted on lesswrong given it’s reputation.
All that said the epistemic hygiene doesn’t seem valid as a system, number 2 for example is impossible to do because everything around you primes you for the experience. Buddhism calls it dependent arising. To be alive is to be affected by things around you.
The segment on memetic transfer is also sketchy as the cited articles don’t say what you think they do. They don’t know how people are affected by it and the methodology has come under fire for being unreliable. In short the field is too new to really say anything about what’s going on. The cited article on the constructive aspect of visual attention also doesn’t support what you draw from it or say anything about attention per se. You are still looking direct at the illusions, just different parts of them.
All in all this post seems short-sighted and making judgments that don’t really follow from the evidence.