I don’t think there was an RCT for DMT vs triptans. It’d be great to have one but I don’t think anyone ran one. There are also legal barriers to running one (which are definitely possible to overcome, but still).
Testimonials and surveys of patients are the best thing we have currently.
Oh interesting, thanks for the comment. I’ll think how better describe migraines then, maybe simply “there is often debilitating pain”.
How bad is a median migraine across entire population? I assumed people generally don’t function well with it, e.g. lie down to wait it out.