Ralph Hull made a reasonable living as a magician milking a card trick he called “The Tuned Deck”...Hull enjoyed subjecting himself to the scrutiny of colleagues who attempted to eliminate, one by one, various explanations by depriving him of the ability to perform a particular sleight of hand. But the real trick was over before it had even begun, for the magic was not in clever fingers but in a clever name. The blatantly singular referent cried out for a blatantly singular explanation, when in reality The Tuned Deck was not one trick but many. The search for a single explanation is what kept this multiply determined illusion so long a mystery.
--Nicholas Epley, “Blackwell Handbook of Judgment and Decision Making”
If the sole determining factor of whether an interaction with a women is desirable is whether they end up attracted to you then, yes, even the most extreme sort of pick up artistry would be unproblematic.
However, if you think that there are other factors that determine whether such an interaction is desirable (such as whether the woman is treated with respect, is not made to feel unpleasant etc) then certain sorts of pick up artistry are extremely distasteful.
For example, let’s hypothetically imagine that women are more attracted to people who make them feel insecure (I take no position on the accuracy of this claim). Sure, it would just be “understanding how women work and adjusting your behaviour to be more attractive to them” if you deliberately made them feel insecure. And sure, this would be no problem if being attractive was the sole determining factor of whether the interaction was desirable. However, if you think women deserve to be treated with respect and not made to feel horrible (presuming not because they are women but just because all humans deserve this) then this interaction is extremely undesirable.
Some discussions of pick up artistry don’t just blur this line but fail to even realise there is a line. To those who think women should be treated with respect, this is extremely concerning.