(...) the term technical is a red flag for me, as it is many times used not for the routine business of implementing ideas but for the parts, ideas and all, which are just hard to understand and many times contain the main novelties.
- Saharon Shelah
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Twitter: @FellowHominid
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So happy to see this post appear! 🔥
The story about operons and the high interconnectedness of prokaryote genomes makes me wonder: bacteria kick out the antibiotic-coding gene after a few hours… but how does it know which gene to kick out?
Does it have a way to tell which genes are more ‘alien’ than others? (Or are we only talking about plasmids here?) I’ve heard it’s hard to genomic manipulate some genomes because the cells keep kicking out new genes
One could speculate there is some sort of mechanism, perhaps epi-genetic, that is able to tell which genes are more alien / new than others somehow?
I’d love to hear your thoughts