You don’t need to go through that much work. When we want to study what happens when a certain protein isn’t expressed we usually don’t remove the relevant gene from the genome but do gene knockdown via siRNA.
If we know all the active transposons we can create a DNA string that codes for a lot of siRNA for all the transposons we are concerned about and only need to do one injection into the genome.
The technology is there. If nobody has done the experiment it’s just the matter of talking anybody with a lab that cares about mice lifespan to run it (and maybe for a grant giver to spend a few hundred thousand).
You don’t need to go through that much work. When we want to study what happens when a certain protein isn’t expressed we usually don’t remove the relevant gene from the genome but do gene knockdown via siRNA.
If we know all the active transposons we can create a DNA string that codes for a lot of siRNA for all the transposons we are concerned about and only need to do one injection into the genome.
The technology is there. If nobody has done the experiment it’s just the matter of talking anybody with a lab that cares about mice lifespan to run it (and maybe for a grant giver to spend a few hundred thousand).