How rational is the path of least resistance?

There is a the­ory of “the path of least re­sis­tance” that im­plies the one should go with the flow. With that in mind, how do you con­tinue to nur­ture the growth re­sult­ing from challenges? Does the ra­tio­nale of the path of least re­sis­tance con­flict with the challenges of life that are re­quired for change?