There’s no good candidate for a simple, legible, easily-obtained, and agreeable-to-most metric. Before-and-after polling of patients is probably closest we can get.
That said, the dimensions of quality that the FDA concerns itself with (including physical functioning, self-reported pain, and other easily- and not-easily-measured things) is likely close enough to “improves quality of life” that it’s not necessary to have a new direction.
Perhaps you could identify some drugs that you think would improve quality of life, and work backwards to the metrics that prove to you that they do so.
That said, the dimensions of quality that the FDA concerns itself with (including physical functioning, self-reported pain, and other easily- and not-easily-measured things) is likely close enough to “improves quality of life” that it’s not necessary to have a new direction.
Athletic performance. Cognitive performance. Work performance. Also ability to accomplish the things needed in every day life to have uh fun..
There’s no good candidate for a simple, legible, easily-obtained, and agreeable-to-most metric. Before-and-after polling of patients is probably closest we can get.
That said, the dimensions of quality that the FDA concerns itself with (including physical functioning, self-reported pain, and other easily- and not-easily-measured things) is likely close enough to “improves quality of life” that it’s not necessary to have a new direction.
Perhaps you could identify some drugs that you think would improve quality of life, and work backwards to the metrics that prove to you that they do so.
Athletic performance. Cognitive performance. Work performance. Also ability to accomplish the things needed in every day life to have uh fun..