The best way is probably to have an excellent investigator rank the research subjects by their quality of life. If you’ve got a good idea about what a high-quality life is, you could probably do the ranking of them yourself.
That sounds like it’s relatively easy to game by the company who chooses the investigators.
Since it’s the FDA that’s doing the regulating, they could pick the investigator. Completely ungameable.
The best way is probably to have an excellent investigator rank the research subjects by their quality of life. If you’ve got a good idea about what a high-quality life is, you could probably do the ranking of them yourself.
That sounds like it’s relatively easy to game by the company who chooses the investigators.
Since it’s the FDA that’s doing the regulating, they could pick the investigator. Completely ungameable.