Night 1: I got to sleep quickly, woke briefly after 1 1⁄2 hours, woke up early again with muscle cramp (I expect this at least to be unrelated). I’d rate as “worse sleep than normal”. Didn’t notice myself being out of distribution for daytime alertness conditioned on sleep.
Night 2: got to sleep quickly, woke early, but sleep quality seemed fine. Not obviously out of distribution for alertness.
Nights 3-8: failed to keep detailed logs. I think I’ve slept quickly every night (good if related), and often woken up early (bad if related). Neither of those is very out of distribution. Been mildly sick which probably confounds things too. Inclined to keep taking it.
I should mention here that I think the “improve sleep onset” dose of 3g just before bed is calibrated for NMDA receptor stimulation, not the improved ROS clearance etc that would improve sleep quality, for which 10g/day (ideally broken up into at least 2 doses with meals) seems like a good place to start. I see no strong reason not to try both, though. And if you want to see over a slightly longer period what 3g/night does instead, that seems like good data to have anyhow.
“Got to sleep quickly” is the main immediate easy to recognize benefit I’d expect from the 3g dose just before bed (unless, of course, you already usually got to sleep quickly).
Yeah, I think I’ll keep trying 3g/night for a bit and then maybe explore 10g/day. That feels like a pretty inconvenient dose to be taking, but so it goes.
I had been wondering how much of the effect comes from the timing and how much comes from just getting more. There must be a time delay in the process of “glycine enters your stomach, makes its way into your bloodstream, gets incorporated into glutathione, and that helps clear ROS”. But I figured, sleep lasts a while, it could well be that the glutathione starts doing its work an hour after you take the glycine; and maybe if you take it earlier in the day, it’s all used in other things by the time you get to sleep.
But “no, 3g just before sleep isn’t enough at the right time to help with sleep” is also not surprising.
Glycine is water soluble and slightly sweet tasting. 10g readily solves in a glass of water.
As it’s sweet it does encourage your body to produce some insulin which could be an issue for some people but probably not for just trying it out for a few weeks for most people.
Night 1: I got to sleep quickly, woke briefly after 1 1⁄2 hours, woke up early again with muscle cramp (I expect this at least to be unrelated). I’d rate as “worse sleep than normal”. Didn’t notice myself being out of distribution for daytime alertness conditioned on sleep.
Night 2: got to sleep quickly, woke early, but sleep quality seemed fine. Not obviously out of distribution for alertness.
Nights 3-8: failed to keep detailed logs. I think I’ve slept quickly every night (good if related), and often woken up early (bad if related). Neither of those is very out of distribution. Been mildly sick which probably confounds things too. Inclined to keep taking it.
I should mention here that I think the “improve sleep onset” dose of 3g just before bed is calibrated for NMDA receptor stimulation, not the improved ROS clearance etc that would improve sleep quality, for which 10g/day (ideally broken up into at least 2 doses with meals) seems like a good place to start. I see no strong reason not to try both, though. And if you want to see over a slightly longer period what 3g/night does instead, that seems like good data to have anyhow.
“Got to sleep quickly” is the main immediate easy to recognize benefit I’d expect from the 3g dose just before bed (unless, of course, you already usually got to sleep quickly).
Yeah, I think I’ll keep trying 3g/night for a bit and then maybe explore 10g/day. That feels like a pretty inconvenient dose to be taking, but so it goes.
I had been wondering how much of the effect comes from the timing and how much comes from just getting more. There must be a time delay in the process of “glycine enters your stomach, makes its way into your bloodstream, gets incorporated into glutathione, and that helps clear ROS”. But I figured, sleep lasts a while, it could well be that the glutathione starts doing its work an hour after you take the glycine; and maybe if you take it earlier in the day, it’s all used in other things by the time you get to sleep.
But “no, 3g just before sleep isn’t enough at the right time to help with sleep” is also not surprising.
Glycine is water soluble and slightly sweet tasting. 10g readily solves in a glass of water.
As it’s sweet it does encourage your body to produce some insulin which could be an issue for some people but probably not for just trying it out for a few weeks for most people.