but there is a great body of work proving that Vit D is beneficial for treating respiratory infection in general [I can cite on request] so unless most respiratory infections secretly involved cytokine storm [which I don’t believe to be true] or Vit D is beneficial in other ways than what you suggest.
Oh that’s entirely plausible. I should have emphasised that this may well be something that’s going on; it certainly doesn’t make it the only thing. Again, I have no expertise in this area—so mainly I’d like people with more knowledge than I to watch the video and draw their own conclusions.
My main takeaway with respect to the RCT in the post is that measurements of the 25-D being low in patients can’t be taken as evidence of deficiency if the 1,25-D levels are simultaneously high. So it’s premature to draw conclusions about non-deficient healthy people being ~92% safer than baseline.
It still seems right to me that not being deficient is important, and that vitamin D treatment is important.
but there is a great body of work proving that Vit D is beneficial for treating respiratory infection in general [I can cite on request] so unless most respiratory infections secretly involved cytokine storm [which I don’t believe to be true] or Vit D is beneficial in other ways than what you suggest.
https://www.lesswrong.com/posts/LwcKYR8bykM6vDHyo/coronavirus-justified-practical-advice-thread?commentId=KEAc428gk4F6Ys3tv
comment above suggested that the benefit is from Vit D prevent the pneumonia from covid from getting worse, and I found the argument persuasive
Oh that’s entirely plausible. I should have emphasised that this may well be something that’s going on; it certainly doesn’t make it the only thing. Again, I have no expertise in this area—so mainly I’d like people with more knowledge than I to watch the video and draw their own conclusions.
My main takeaway with respect to the RCT in the post is that measurements of the 25-D being low in patients can’t be taken as evidence of deficiency if the 1,25-D levels are simultaneously high. So it’s premature to draw conclusions about non-deficient healthy people being ~92% safer than baseline.
It still seems right to me that not being deficient is important, and that vitamin D treatment is important.