I am not overly concerned about regulations. The research can always be done in friendly jurisdictions. I don’t suppose the US would charge people for conducting clinical trials abroad (which are legal in the country where they were performed).
Places I agree with you:
The trials can be risky, and it can be hard (but not impossible) to get approval for one.
It’s likely that the link between DYT1 and IQ doesn’t exist.
It can be almost impossible to get US approval
Places I potentially disagree with you:
I predict that it’s possible to come to a robust theory on how dystonia and IQ is linked prior to experimentation.
I believe that difficulty of US approval is not blocking.
I believe that interested funders definitely exist
I do not anticipate issues with hiring researchers
Edit: I would be interested in how risky we exactly expect the trials to be, and what we can do to reduce this risk.
I am not overly concerned about regulations. The research can always be done in friendly jurisdictions. I don’t suppose the US would charge people for conducting clinical trials abroad (which are legal in the country where they were performed).
Places I agree with you:
The trials can be risky, and it can be hard (but not impossible) to get approval for one.
It’s likely that the link between DYT1 and IQ doesn’t exist.
It can be almost impossible to get US approval
Places I potentially disagree with you:
I predict that it’s possible to come to a robust theory on how dystonia and IQ is linked prior to experimentation.
I believe that difficulty of US approval is not blocking.
I believe that interested funders definitely exist
I do not anticipate issues with hiring researchers
Edit: I would be interested in how risky we exactly expect the trials to be, and what we can do to reduce this risk.