Experimentally, NIST tested a bunch of tests 2021 and while they weren’t great (and many did not meet NIST’s target of ± 5% bias) they overall seemed to be OK-ish if your purpose is just to decide If your levels are low: (Fig. 3 and Fig. 4) https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=930349
I’m not sure what’s going on because this NIST test seems to include many of the same vendors shown in your figure. One possibility is that there’s a skill component to doing the assays? In the above paper, they were seemingly done by NIST. Maybe in your figure the assays were done by different people? It seems possible that this could lead to some extra error.
Thanks. I’m having trouble verifying this, though. At a glance, CLIA-verification seems to require both precision (consistency) and accuracy: https://www.cms.gov/regulations-and-guidance/legislation/clia/downloads/6064bk.pdf
Experimentally, NIST tested a bunch of tests 2021 and while they weren’t great (and many did not meet NIST’s target of ± 5% bias) they overall seemed to be OK-ish if your purpose is just to decide If your levels are low: (Fig. 3 and Fig. 4) https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=930349
I’m not sure what’s going on because this NIST test seems to include many of the same vendors shown in your figure. One possibility is that there’s a skill component to doing the assays? In the above paper, they were seemingly done by NIST. Maybe in your figure the assays were done by different people? It seems possible that this could lead to some extra error.