Re: psychedelic enthusiasts.overstating effects. I recommend going for the primary sources and looking up testimonials from cluster headache patients!
Yeah… I’m trying to beware surprising and suspicious convergence here. “Local psychedelics enthusiasts discover that psychedelics are the cure to the worst conditions known to humanity, more at 11.”
This is, in some sense, a cheap and kind of mean heuristic, but I wanted to flag the suspicion. I might go and read some testimonials, but nothing beats a good ol’ RCT[1]. I don’t want to be the person who’s like “you need more research before you advocate” and I’m looking forward to putting DMT-variants head-to-head in an experiment with known medical treatments for cluster headaches.
Actually not true, we could & should try to design successors to the RCT, but they’ll go in the direction of “Thompson-sample from the posterior distribution in some bandit setup” as opposed to “more anecdata”.
I don’t think there was an RCT for DMT vs triptans. It’d be great to have one but I don’t think anyone ran one. There are also legal barriers to running one (which are definitely possible to overcome, but still).
Testimonials and surveys of patients are the best thing we have currently.
Yeah… I’m trying to beware surprising and suspicious convergence here. “Local psychedelics enthusiasts discover that psychedelics are the cure to the worst conditions known to humanity, more at 11.”
This is, in some sense, a cheap and kind of mean heuristic, but I wanted to flag the suspicion. I might go and read some testimonials, but nothing beats a good ol’ RCT [1] . I don’t want to be the person who’s like “you need more research before you advocate” and I’m looking forward to putting DMT-variants head-to-head in an experiment with known medical treatments for cluster headaches.
Actually not true, we could & should try to design successors to the RCT, but they’ll go in the direction of “Thompson-sample from the posterior distribution in some bandit setup” as opposed to “more anecdata”.
I don’t think there was an RCT for DMT vs triptans. It’d be great to have one but I don’t think anyone ran one. There are also legal barriers to running one (which are definitely possible to overcome, but still).
Testimonials and surveys of patients are the best thing we have currently.