Metformin as a rationalist win. For several years I have been taking 2 grams of Metformin a day for anti-aging reasons. There is a vast literature on Metformin and as a mere economist I’m unqualified to summarize it. But my (skin-in-the-game) guess is that all adults over 40 (and perhaps simply all adults) should be taking Metformin and I would love if someone with a bio-background wrote up a Metformin literature review understandable to those of us who understand statistics but not much about medicine. The reason why Metformin might be universally beneficial and yet not generally taken is because no one holds a patent on Metformin (it’s cheap), in the US you need a prescription to get it, and the medical system doesn’t consider aging to be a disease.
I have not heard about anti aging effects but apart from standard indications, I know it helps to loose weight and to an extent prevents obesity. In a oblique manner it may be also a way to deage yourself but… How do you know about the anti-aging effect and what does it mean really? It doesn’t reverse time obviously.
I am sorry, to doubt. It just seems to be an extraordinary claim.
Much of the harm of aging is the increased likelihood of getting many diseases such as cancer, heart disease, alzheimer’s, and strokes as you age. From my limited understanding, Metformin reduces the age-adjusted chance of getting many of these diseases and thus it’s reasonable, I believe, to say that Metformin has anti-aging effects.
Oh, ok, I get it slows down ageing. I hoped that you may know of some evidence that it reverses degeneration. in retrospect, I can see that you wrote anti and not de ageing , so the misunderstanding is entirely my fault. Thanks for your clarification 😊
Metformin as a rationalist win. For several years I have been taking 2 grams of Metformin a day for anti-aging reasons. There is a vast literature on Metformin and as a mere economist I’m unqualified to summarize it. But my (skin-in-the-game) guess is that all adults over 40 (and perhaps simply all adults) should be taking Metformin and I would love if someone with a bio-background wrote up a Metformin literature review understandable to those of us who understand statistics but not much about medicine. The reason why Metformin might be universally beneficial and yet not generally taken is because no one holds a patent on Metformin (it’s cheap), in the US you need a prescription to get it, and the medical system doesn’t consider aging to be a disease.
Hello James.
I have not heard about anti aging effects but apart from standard indications, I know it helps to loose weight and to an extent prevents obesity. In a oblique manner it may be also a way to deage yourself but… How do you know about the anti-aging effect and what does it mean really? It doesn’t reverse time obviously.
I am sorry, to doubt. It just seems to be an extraordinary claim.
Best regards, Piotr, anaesthetist intensivist.
Much of the harm of aging is the increased likelihood of getting many diseases such as cancer, heart disease, alzheimer’s, and strokes as you age. From my limited understanding, Metformin reduces the age-adjusted chance of getting many of these diseases and thus it’s reasonable, I believe, to say that Metformin has anti-aging effects.
Oh, ok, I get it slows down ageing. I hoped that you may know of some evidence that it reverses degeneration. in retrospect, I can see that you wrote anti and not de ageing , so the misunderstanding is entirely my fault. Thanks for your clarification 😊
Berberine supposedly has many of the same effects and potentially fewer side effects and is OTC.
Have you by any chance seen this? (It’s not published yet, but I read it a year ago and thought it was quite good, as far as I can judge such things).
Thanks!