Have you tried any of the Agonists? Did they work for you?
The reason no one seems excited to work on this is that very few people, who didnt initially sleep way too much, report they managed to substantially reduce their need for sleep without side effects. Everyone already knows about common* stimulants like modafinal and amphetamine. People also know about sleep hygeine. Both work. But neither radically reduces the need for sleep in healthy people. When people use stimulants in high doses for a long time to reduce sleep they commonly reprort severe adverse effects.
But anything is possible and orexin agonists are not commonly discussed at all. So maybe they work. So im quite serious when I ask if you tried them! Historically much science started with n=1.
I think there’s a substantial chance that orexin agonists are “just stimulants” and you can’t reduce sleep need much with them. But short sleepers prove it’s biologically possible and I want to encourage people to start working on this.
Have you tried any of the Agonists? Did they work for you?
The reason no one seems excited to work on this is that very few people, who didnt initially sleep way too much, report they managed to substantially reduce their need for sleep without side effects. Everyone already knows about common* stimulants like modafinal and amphetamine. People also know about sleep hygeine. Both work. But neither radically reduces the need for sleep in healthy people. When people use stimulants in high doses for a long time to reduce sleep they commonly reprort severe adverse effects.
But anything is possible and orexin agonists are not commonly discussed at all. So maybe they work. So im quite serious when I ask if you tried them! Historically much science started with n=1.
We are fundraising for a self-experiment soon!
I think there’s a substantial chance that orexin agonists are “just stimulants” and you can’t reduce sleep need much with them. But short sleepers prove it’s biologically possible and I want to encourage people to start working on this.