I could have imagined a case where the weight-loss effects were coming solely from the phentermine, with topiramate added to the combination for other reasons. But it having its own independent/​added effect makes sense. For the person I know taking it, her appetite does seem quite reduced since switching from amitriptyline (I think that one increases appetite, so there will have been a double-effect from switching off that and onto something that suppresses it)
The brain fog is unfortunate, but also still less bad overall than the migraines were.
God to know, thanks.
I could have imagined a case where the weight-loss effects were coming solely from the phentermine, with topiramate added to the combination for other reasons. But it having its own independent/​added effect makes sense. For the person I know taking it, her appetite does seem quite reduced since switching from amitriptyline (I think that one increases appetite, so there will have been a double-effect from switching off that and onto something that suppresses it)
The brain fog is unfortunate, but also still less bad overall than the migraines were.