An alternate interpretation of the result is that Beta just didn’t have much immune escape. That fact that it was crushed by Delta suggests that. The vaccine produced antibodies that were more tuned to Beta than those from the original vaccine, but the difference was slight, just a factor of 2. We won’t know about OAS until we have a variant with real immune escape, which may well be Omicron. But I’m not worried about OAS because it’s a lower order effect.
An alternate interpretation of the result is that Beta just didn’t have much immune escape. That fact that it was crushed by Delta suggests that. The vaccine produced antibodies that were more tuned to Beta than those from the original vaccine, but the difference was slight, just a factor of 2. We won’t know about OAS until we have a variant with real immune escape, which may well be Omicron. But I’m not worried about OAS because it’s a lower order effect.