From the comments, PZ elaborates: “Andrew G: No, you don’t understand. Part of this magical “scan” has to include vast amounts of data on the physics of the entity…pieces which will interact in complex ways with each other and the environment. Unless you’re also planning to build a vastly sped up model of the whole universe, you’re going to have a simulation of brain running very fast in a sensory deprivation tank.
Or do you really think you can understand how the brain works in complete isolation from physiology, endocrinology, and sensation?”
Seems like PZ is dismissing the feasibility of computation by assuming that computation has to be perfectly literal. To make a chemistry analogy here, one does not have to model the quantum mechanics and the dynamics of every single molecule in a beaker of water in order to simulate the kinetics of a reaction in water. One does not need to replicate the chemical entirety of the neuron in silico; one merely needs to replicate the neuron’s stimulus-response patterns.
Oops, didn’t see a further comment below: In response to a comment, ” I still don’t understand why biologists insist that you have to do a perfect simulation, down to the smallest molecule, and then state the obvious fact that it’s not going to happen.”, PZ says this:
“Errm, because that’s what the singularitarians we’re critiquing are proposing? This whole slice-and-scan proposal is all about recreating the physical components of the brain in a virtual space, without bothering to understand how those components work. We’re telling you that approach requires an awfully fine-grained simulation.
An alternative would be to, for instance, break down the brain into components, figure out what the inputs and outputs to, say, the nucleus accumbens are, and then model how that tissue processes it all (that approach is being taken with models of portions of the hippocampus). That approach doesn’t require a detailed knowledge of what every molecule in the tissue is doing.
But the method described here is a brute force dismantling and reconstruction of every cell in the brain. That requires details of every molecule.”
Still seems like a straw man.