And again, in conversations that fit this pattern, what I notice is that everything the person expresses indicates they want to make this change. They only say positive things about it. They seem eager and hopeful. They give reasons in favor of doing it, and reasons against not doing it.
A somewhat smaller factor in the psychology of this I believe is not quite mentioned by the previous comments (not-yet-verbalized ways in which things could go wrong, general anxiety about something not yet being considered) is that from the speaker’s perspective, they have a plan laid in front of them with nothing but apparent upsides, which leads to a natural sense of suspicion. For example, if somebody saw an advertised service that touted nothing but benefits, one would naturally look for the “catch”—some factor showing how the service wasn’t what it was presented to be. Likewise, in the case of a personal choice that seems entirely positive, perhaps the speaker feels as though there should be a catch to their plan. And, they may experience discomfort from not knowing what it may be.
The list provided shows a lot of future empirical questions whose answers will influence ethical theories, but there may also be some interesting past examples already. For example, the Theory of Evolution showing how humans and animals are not different in kind likely played a supporting role in animal welfare. Going back even further, many ancient cultures believed that certain diseases were a sign of either divine punishment or something otherwise supernatural, which we now know is not true thanks to our modern medical science.
The linked article on Long Reflection suggests rather large timescales (1000+ years in certain cases), but since you had mentioned what seems like an accelerating rate of philosophical progress (e.g. the fact that >1/2 of the thought experiments on Wikipedia’s list came after 1960), I’m not entirely sure that humanity would actually have to spend that long before either solving ethics, or at least generally agreeing on immediate next steps. If we presume that at least part of this acceleration exists independently of our recent technological advancement—assuming that a Long Reflection involves a pause in at least some respects, namely advanced AI—then it might not be that long for another doubling in thought experiments / general philosophical output to occur. In summary, even if humanity embarks on a Long Reflection with the intention of it lasting a very long time, I find it plausible that 20-50 years down the line, they may have already accumulated enough knowledge to at least make some changes to the world, and then debate next steps from a new starting point. During a reflection of that length, it is still very much possible for amoral actors to gain more power, but I would consider it less of a risk than with the original timescales.
Overall, I generally agree with your implications for the future, and share your concern about whether those in power will care about others, which seems like a more challenging issue to address as it is difficult to imagine ways to improve our chances on an issue of personal motivation.