I don’t know if author will even see this comment, but beyond the mainstream theories of antagonistic pleiotropy and damage accumulation, the reader may find it interesting to explore the concept of programmed aging as an adaptation to combat pathogens. IMHO, this is a better example to defend the position than thymic involution, because it makes a much stronger case for the existence of a ‘program’.
I don’t know if author will even see this comment, but beyond the mainstream theories of antagonistic pleiotropy and damage accumulation, the reader may find it interesting to explore the concept of programmed aging as an adaptation to combat pathogens. IMHO, this is a better example to defend the position than thymic involution, because it makes a much stronger case for the existence of a ‘program’.