Recent Lyme-related news suggests that such cases may be caused by repeated infections.
This makes sense — people who have gotten Lyme are not much more likely than others to move out of the Northeast U.S. or stay out of the woods, those being pretty much how to avoid exposure.
The article I cited suffers somewhat from sampling error though. You can’t really sample from those with migrating rashes—and then draw conclusions about the prevalence of repeat infections as an explanation for chronic cases.
This makes sense — people who have gotten Lyme are not much more likely than others to move out of the Northeast U.S. or stay out of the woods, those being pretty much how to avoid exposure.
The article I cited suffers somewhat from sampling error though. You can’t really sample from those with migrating rashes—and then draw conclusions about the prevalence of repeat infections as an explanation for chronic cases.