Besides this mistake, the original FDA study seems iffy to me. Look at their graph—how in the world do they draw 95% prediction limits in such a way that 19 out of their 32 sample averages (60%!) are outside of their 95% interval?
I’ve looked into the study, but it doesn’t point to a specific location in IOM’s document, which is huge. My tentative explanation is that those studies that fell out of the interval have a very small size, but I cannot say for certain.
Besides this mistake, the original FDA study seems iffy to me. Look at their graph—how in the world do they draw 95% prediction limits in such a way that 19 out of their 32 sample averages (60%!) are outside of their 95% interval?
I’ve looked into the study, but it doesn’t point to a specific location in IOM’s document, which is huge. My tentative explanation is that those studies that fell out of the interval have a very small size, but I cannot say for certain.