I don’t know about heart disease and cancer risk and I’m in roughly the same epistemic position as you on that.
For plain old fat loss, though, there’s more reason to believe that more fat and protein compared to carbohydrates is effective. First, that’s what athletes and their nutrition coaches do—it’s always useful to look at the practices of people whose livelihood depends on objective success. Second, I’ve read a fair number of CDC studies showing that diets have modest to zero effect—and usually the test diets do not have a high protein + fat to carb ratio. That’s weak evidence, but evidence: the stuff that doesn’t work is not the candidate in question. Third, it just makes sense that simple sugars break down into glucose faster than anything else, which means a quick spike in blood sugar instead of slow release over time, which means you’ll be hungry soon after. No, plausible mechanisms aren’t science, but they help. Fourth, it’s easy enough to perform the experiment yourself for three months and see what happens.
I haven’t read the book either.
I don’t know about heart disease and cancer risk and I’m in roughly the same epistemic position as you on that.
For plain old fat loss, though, there’s more reason to believe that more fat and protein compared to carbohydrates is effective. First, that’s what athletes and their nutrition coaches do—it’s always useful to look at the practices of people whose livelihood depends on objective success. Second, I’ve read a fair number of CDC studies showing that diets have modest to zero effect—and usually the test diets do not have a high protein + fat to carb ratio. That’s weak evidence, but evidence: the stuff that doesn’t work is not the candidate in question. Third, it just makes sense that simple sugars break down into glucose faster than anything else, which means a quick spike in blood sugar instead of slow release over time, which means you’ll be hungry soon after. No, plausible mechanisms aren’t science, but they help. Fourth, it’s easy enough to perform the experiment yourself for three months and see what happens.