Depending on how much you want to invest in aesthetics vs. simply producing a user-friendly GUI, Visual Studio takes almost all of the tricky work out of producing basic GUIs (whether you’re working in Visual Basic or C++) and is an easy go-to solution especially since it’s now free for individuals, even for commercial use (still requires Windows though; I don’t have a lot of experience writing GUI apps for other desktop OSes). The results will likely look somewhere between utilitarian and just ugly until/unless you learn some UI design aesthetics and expend the effort to apply them, but even there tools such as Blend exist to help out (especially on mobile, but some of that stuff can be applied to PC software too).
Depending on how much you want to invest in aesthetics vs. simply producing a user-friendly GUI, Visual Studio takes almost all of the tricky work out of producing basic GUIs (whether you’re working in Visual Basic or C++) and is an easy go-to solution especially since it’s now free for individuals, even for commercial use (still requires Windows though; I don’t have a lot of experience writing GUI apps for other desktop OSes). The results will likely look somewhere between utilitarian and just ugly until/unless you learn some UI design aesthetics and expend the effort to apply them, but even there tools such as Blend exist to help out (especially on mobile, but some of that stuff can be applied to PC software too).