I’m confused why these would be described as “challenge” RCTs, and worry that the term will create broader confusion in the movement to support challenge trials for disease. In the usual clinical context, the word “challenge” in “human challenge trial” refers to the step of introducing the “challenge” of a bad thing (e.g., an infectious agent) to the subject, to see if the treatment protects them from it. I don’t know what a “challenge” trial testing the effects of veganism looks like?
(I’m generally positive on the idea of trialing more things; my confusion+comment is just restricted to the naming being proposed here.)
Thanks, I agree with this and it’s probably not good branding anyway.
I was thinking the “challenge” was just doing the intervention (e.g. being vegan), but agree that the framing is confusing since it refers to something different in the clinical context. I will edit my shortforms to reflect this updated view.
I’m confused why these would be described as “challenge” RCTs, and worry that the term will create broader confusion in the movement to support challenge trials for disease. In the usual clinical context, the word “challenge” in “human challenge trial” refers to the step of introducing the “challenge” of a bad thing (e.g., an infectious agent) to the subject, to see if the treatment protects them from it. I don’t know what a “challenge” trial testing the effects of veganism looks like?
(I’m generally positive on the idea of trialing more things; my confusion+comment is just restricted to the naming being proposed here.)
Thanks, I agree with this and it’s probably not good branding anyway.
I was thinking the “challenge” was just doing the intervention (e.g. being vegan), but agree that the framing is confusing since it refers to something different in the clinical context. I will edit my shortforms to reflect this updated view.