4-AcO-DMT and most other psychedelics also last on the order of 8 hours (or more), while inhaled / injected DMT lasts ~20 minutes.
Normally, ingested DMT has no pharmacological activity because monoamine oxidase (MAO) in the body will break it down before it has any effect. The likely reason is that DMT is endogenous.
Ayahuasca is an ingested DMT extract that also contains a natural MAO-inhibitor. (“Pharmahuasca” is an analogue of it that uses ingestion of purified DMT plus an MAO-inhibitor in pill form).
A sub-impairment dose of DMT sounds like the least invasive treatment for this in particular.
4-AcO-DMT and most other psychedelics also last on the order of 8 hours (or more), while inhaled / injected DMT lasts ~20 minutes.
Normally, ingested DMT has no pharmacological activity because monoamine oxidase (MAO) in the body will break it down before it has any effect. The likely reason is that DMT is endogenous.
Ayahuasca is an ingested DMT extract that also contains a natural MAO-inhibitor. (“Pharmahuasca” is an analogue of it that uses ingestion of purified DMT plus an MAO-inhibitor in pill form).
A sub-impairment dose of DMT sounds like the least invasive treatment for this in particular.