I’m not even sure what the distinction between the first and second cases is besides scale of uploading—is there one
It’s scale, just in the first case we’re basically stuck forever at the status quo until someone makes a neurological discovery that reveals our mistake versus frank extinction leaving no living humans to observe. I suppose that if the entire planet isn’t uploaded, the mistake might still be discoverable from animal research. There is no guarantee that this missing ingredient will be the only one.
It’s scale, just in the first case we’re basically stuck forever at the status quo until someone makes a neurological discovery that reveals our mistake versus frank extinction leaving no living humans to observe. I suppose that if the entire planet isn’t uploaded, the mistake might still be discoverable from animal research. There is no guarantee that this missing ingredient will be the only one.