For those wondering about the safety of introducing new bacteria that “outcompete” existing bacteria, Aaron Silverbook’s proposal has a safety review FAQ that, indeed, answered a bunch of my questions, starting with an anonymous question in the comments sidebar:
Q: Why is the GMO bacteria guaranteed to outcompete the native bacteria? Does it reproduce more quickly or something?
A: JH1140 secretes Mutacin 1140, a natural bacteriocin which kills native S mutans
Which is a pretty reassuring answer compared to the other alternatives one might imagine, and lends itself to generalization.
For those wondering about the safety of introducing new bacteria that “outcompete” existing bacteria, Aaron Silverbook’s proposal has a safety review FAQ that, indeed, answered a bunch of my questions, starting with an anonymous question in the comments sidebar:
Which is a pretty reassuring answer compared to the other alternatives one might imagine, and lends itself to generalization.