Caveats: this is all vibes based. The following LEGALLY NOT ADVICE is pretty low-risk and easy, but I have no idea if it will actually work. Some people have already tried this (look up Nasal Microbiome Transplant)
Best guess: your nasal microbiome is in a low diversity disease state similar to C. difficile infections in the gut. Hitting it with antibiotics doesn’t work because the staph just resists and rebounds faster than anything else.
What I would do in your situation: use the garlic nasal spray, leave it an hour or so, then (the unpleasant part) put someone else’s snot up your nose to recolonize your nasal cavity with a healthy, diverse microbiome.
The important other question is whether you should come off the antibiotics for a bit. This is higher risk than any other part of the advice (since the antibiotics are for maintenance) but might be necessary: if you stay on the antibiotics, you might just kill off all your brand new microbiome.
! This actually makes a GREAT deal of sense since learning that raw apple cider vinegar contains its own biofilm, which probably accounts for some of how it colloquially helps alleviate insulin resistance [ Horiguti found in 1975 that mechanical nasopharyngeal abrasion restored insulin response in diabetics ].
C. diff is the classic case, fecal transplants are really well established there as the good treatment for antibiotic-induced infections at this point. I learned about it reading about the microbiome a few years ago.
FWIW I actually also ran the idea past my partner who works in microbial community modelling (though not in anything medical related, they run simulations) and it was roughly:
Me: I’m looking up nasal microbiome transplants
Them: I’m not sure that makes sense, the nasal microbiome is normally fairly low-diversity, it’s not the same as the gut
I should have said, I’d known about fecal transplants being miracle cures per se, that was the main reason I’d been able to come up with that hypothesis for why drinking raw ACV worked better than drinking distilled vinegar.
It just seemed like a non-obvious [ though valid ] inference to make, and I’d been wondering if I’d missed an existing nasal microbiome or general tissue microbiome literature.
Caveats: this is all vibes based. The following LEGALLY NOT ADVICE is pretty low-risk and easy, but I have no idea if it will actually work. Some people have already tried this (look up Nasal Microbiome Transplant)
Best guess: your nasal microbiome is in a low diversity disease state similar to C. difficile infections in the gut. Hitting it with antibiotics doesn’t work because the staph just resists and rebounds faster than anything else.
What I would do in your situation: use the garlic nasal spray, leave it an hour or so, then (the unpleasant part) put someone else’s snot up your nose to recolonize your nasal cavity with a healthy, diverse microbiome.
The important other question is whether you should come off the antibiotics for a bit. This is higher risk than any other part of the advice (since the antibiotics are for maintenance) but might be necessary: if you stay on the antibiotics, you might just kill off all your brand new microbiome.
! This actually makes a GREAT deal of sense since learning that raw apple cider vinegar contains its own biofilm, which probably accounts for some of how it colloquially helps alleviate insulin resistance [ Horiguti found in 1975 that mechanical nasopharyngeal abrasion restored insulin response in diabetics ].
How did you learn of this class of problem?
C. diff is the classic case, fecal transplants are really well established there as the good treatment for antibiotic-induced infections at this point. I learned about it reading about the microbiome a few years ago.
FWIW I actually also ran the idea past my partner who works in microbial community modelling (though not in anything medical related, they run simulations) and it was roughly:
I should have said, I’d known about fecal transplants being miracle cures per se, that was the main reason I’d been able to come up with that hypothesis for why drinking raw ACV worked better than drinking distilled vinegar.
It just seemed like a non-obvious [ though valid ] inference to make, and I’d been wondering if I’d missed an existing nasal microbiome or general tissue microbiome literature.
But I guess you just had a sensible idea.
Edit: It’s a thing! [ Link ], [ link ]