Changing the dose of a medication does not necessarily result in linear effects. There are nonlinearities introduced by e.g. one receptor type being saturated before another one. This phenomenon also applies to polypharmacy.
I would also like to note that θ∗ is estimated not by some objective standard, but by θ0. There’s no guarantee that it remains in place as you start shifting θ.
In practice, we track our level of suffering and respond to it by trying to reduce it to acceptable levels, which is easier than trying to converge onto a hypothetical global optimum. For some, this state is reached with just one medication, for others it takes more, and for some this paradigm doesn’t produce any results.
Changing the dose of a medication does not necessarily result in linear effects. There are nonlinearities introduced by e.g. one receptor type being saturated before another one. This phenomenon also applies to polypharmacy.
I would also like to note that θ∗ is estimated not by some objective standard, but by θ0. There’s no guarantee that it remains in place as you start shifting θ.
In practice, we track our level of suffering and respond to it by trying to reduce it to acceptable levels, which is easier than trying to converge onto a hypothetical global optimum. For some, this state is reached with just one medication, for others it takes more, and for some this paradigm doesn’t produce any results.