With such highly subjective soft outcomes a lot depends on the way the question is phrased and interpreted (if self-reporting). Thus comparing different populations and studies is almost impossible without really carefully digging into the original publications and even then it is fraught with problems.
If I have a rash post-vaccine and I go to see my GP or pharamcist, am I seeking medical help and is this worrisome? If I get up and later realize that I need to lie down or else I will faint (vasovagal syncope, around one in ten people have some form of needle phobia), am I seeking medical help for a side-effect? Technically yes, but a saline injection would cause the same. If I have asthma or hayfever, issues with breathing, and later misattribute this to the vaccine, is this a side-effect? (around 1 in 10 people or so have asthma)
Finally, you cannot compare the serious side-effects in a trial (if this CDC figure really comes from a trial) with mild self-reported side-effects from Israel or American postmarketing surveillance. Trial participants will be monitored closely and will include a large number of at risk indiviudals (>60yo) so it is again a statistical artifact of data collection.
IMHO all the data is worthless without a very well-matched control group.
With such highly subjective soft outcomes a lot depends on the way the question is phrased and interpreted (if self-reporting). Thus comparing different populations and studies is almost impossible without really carefully digging into the original publications and even then it is fraught with problems.
If I have a rash post-vaccine and I go to see my GP or pharamcist, am I seeking medical help and is this worrisome? If I get up and later realize that I need to lie down or else I will faint (vasovagal syncope, around one in ten people have some form of needle phobia), am I seeking medical help for a side-effect? Technically yes, but a saline injection would cause the same. If I have asthma or hayfever, issues with breathing, and later misattribute this to the vaccine, is this a side-effect? (around 1 in 10 people or so have asthma)
Finally, you cannot compare the serious side-effects in a trial (if this CDC figure really comes from a trial) with mild self-reported side-effects from Israel or American postmarketing surveillance. Trial participants will be monitored closely and will include a large number of at risk indiviudals (>60yo) so it is again a statistical artifact of data collection.
IMHO all the data is worthless without a very well-matched control group.