My favorite theory, supported by some evidence but I haven’t dug in. It matches my experience and understanding of general (sober) cortical functioning:
Hallocinogens strengthen top-down and lateral connections relative to bottom-up sensory connections. That makes imagination/hallucinations more stable, and sensory input weaker so driving activity in global workspace less.
My favorite theory, supported by some evidence but I haven’t dug in. It matches my experience and understanding of general (sober) cortical functioning:
Hallocinogens strengthen top-down and lateral connections relative to bottom-up sensory connections. That makes imagination/hallucinations more stable, and sensory input weaker so driving activity in global workspace less.