That, to me, seems to assume that those areas end up with a locally greater estrogen concentration (for all that summarizing a whole family of molecules related primarily by their signalling effects, can even sensibly be summarized by a single “concentration”), which I’m not actually sure is the case.
It seems to make intuitive sense that a chemical would be most concentrated near its site of introduction into the body, but then I can also think of specific counterexamples. Lead, for example, pools in the skeleton, and almost certainly isn’t being (originally) introduced into the body via the skeleton.
That, to me, seems to assume that those areas end up with a locally greater estrogen concentration (for all that summarizing a whole family of molecules related primarily by their signalling effects, can even sensibly be summarized by a single “concentration”), which I’m not actually sure is the case.
It seems to make intuitive sense that a chemical would be most concentrated near its site of introduction into the body, but then I can also think of specific counterexamples. Lead, for example, pools in the skeleton, and almost certainly isn’t being (originally) introduced into the body via the skeleton.