Anyone trying to use super-resolution microscopy techniques without or alongside expansion? Or is that still under “microscopes too expensive” according to popular wisdom? I guess yeah, trying to modulate the phase of polarized light so you can get extra spatial data from the Fourier transform (or whatever) sounds expensive.
I can’t say that I have heard of anyone doing that specifically for connectomics. I would not be surprised if I just missed it this paper (already in the post) or it is being done for other biological research but is too expensive for connectomics. I would also recommend looking at this guy’s new lab/old work for another place to start.
Anyone trying to use super-resolution microscopy techniques without or alongside expansion? Or is that still under “microscopes too expensive” according to popular wisdom? I guess yeah, trying to modulate the phase of polarized light so you can get extra spatial data from the Fourier transform (or whatever) sounds expensive.
I can’t say that I have heard of anyone doing that specifically for connectomics. I would not be surprised if I just missed it this paper (already in the post) or it is being done for other biological research but is too expensive for connectomics. I would also recommend looking at this guy’s new lab/old work for another place to start.