I’d guess it’s of limited utility—there’s very little good information about all of the effects of this sort of HRT (a very common conversation among trans folks is what effects the doctors never mentioned).
A lot of human sex variation is down to your hormones, particularly during puberty—the x-vs-y chromosomes control much less than you think (the phenotypical development of the penis/testes combo is controlled by the SRY gene; sometimes you get phenotypically “male” folks with an XX pair where the SRY gene has translocated, or XY phenotypically “female” folks without the SRY gene, as well as XY and a functioning SRY gene but who develop as phenotypic “females” anyway. Genetic traits that aren’t themselves sex-linked can nonetheless be strongly affected by the difference hormones make—this is why trans women grow breasts and trans men often find theirs shrinking; it’s also probably why my sense of smell shifted, since that can be rather strongly hereditary and my mother has a very strong sense of smell (enough she’d frequently get headaches in the vicinity of perfume).
I’d guess it’s of limited utility—there’s very little good information about all of the effects of this sort of HRT (a very common conversation among trans folks is what effects the doctors never mentioned).
A lot of human sex variation is down to your hormones, particularly during puberty—the x-vs-y chromosomes control much less than you think (the phenotypical development of the penis/testes combo is controlled by the SRY gene; sometimes you get phenotypically “male” folks with an XX pair where the SRY gene has translocated, or XY phenotypically “female” folks without the SRY gene, as well as XY and a functioning SRY gene but who develop as phenotypic “females” anyway. Genetic traits that aren’t themselves sex-linked can nonetheless be strongly affected by the difference hormones make—this is why trans women grow breasts and trans men often find theirs shrinking; it’s also probably why my sense of smell shifted, since that can be rather strongly hereditary and my mother has a very strong sense of smell (enough she’d frequently get headaches in the vicinity of perfume).