and a recent study in which only 15% of the genetic basis for height (known to be >80% responsible
Note that the proportion explained has been scaling very nicely with increasing sample size, (going from ~0 to current levels over about an order of magnitude scaling in sample size, and with several orders of magnitude left to go), and that the efficacy of a single generation of embryo selection goes with the standard deviation, not the variance, so one should take the square root of “heritability explained” numbers to estimate efficacy.
Also see recent genetic results such as this indicating that common variants are adequate, given larger sample sizes.
Note that the proportion explained has been scaling very nicely with increasing sample size, (going from ~0 to current levels over about an order of magnitude scaling in sample size, and with several orders of magnitude left to go), and that the efficacy of a single generation of embryo selection goes with the standard deviation, not the variance, so one should take the square root of “heritability explained” numbers to estimate efficacy.
Also see recent genetic results such as this indicating that common variants are adequate, given larger sample sizes.