Your problem, I think, has not to do with nihilism, but rather with narcissism. (If none of it’s about anything, then certainly none of it’s about you.)
Regarding the quest for mind-altering experiences I lay that at the feet of the same drive that causes us to want to control our environment, including that of our mind. Some folks just don’t know when to quit. Depression is simply self-flattery. Get over it. If you’re able.
And then back to the point: one trap laid before us by our narcissism is that we think we “know” as much as those who came before us who themselves knew so little. A beginning? A cold death in the void? Do we merely flatter ourselves that the fashions of fashionable thinking are more true than those that came before, rather than just a slightly better approximation?
And to the author’s point: whatever there is, or isn’t, out there, beyond there—I agree that happiness is found in salience. Excitement. Doing. Changing. Becoming.