Interesting to know more about the CFS literature here. Like you, I haven’t found as much good research on it, at least with a quick search. (Though there’s at least one pretty canonical reference connecting chronic fatigue and nociplastic pain FWIW.)
The research on neuroplastic pain seems to have a stronger evidence base. For example, some studies have ‘very large’ effect sizes (compared to placebo), publications with thousands of citations or in top tier journals, official recognition by the leading scientific body on pain research (IASP), and key note talks at the mainstream academic conferences on pain research.
Spontaneous healing and placebo effects happen all the time of course. But in the cases I know, it was often very unlikely to happen at the exact time of treatment. Clear improvement was often timed precisely to the day, hour or even minute of treatments. In my case, a single psychotherapy session brought me from ~25% to ~85% improvement for leg pain, in both knees at once, after it lasted for years. Similar things happened with other pains in a short amount of time after they lasted for between 4 to 30 months.
> Lastly, ignoring symptoms can be pretty dangerous so I recommend caution with the approach
I also fear that knowing about neuroplastic pain will lead certain types of people to ignore physical problems and suffer serious damage.
For what it’s worth, ME/CFS (a disease/cluster of specific symptoms) is quite different from idiopathic chronic fatigue (a single symptom). Confusing the two is one of the major issues in the literature. Many people with ME/CFS, like I, don’t even have ‘feeling tired’ as a symptom. Which is why I avoid the term CFS.
Interesting to know more about the CFS literature here. Like you, I haven’t found as much good research on it, at least with a quick search. (Though there’s at least one pretty canonical reference connecting chronic fatigue and nociplastic pain FWIW.)
The research on neuroplastic pain seems to have a stronger evidence base. For example, some studies have ‘very large’ effect sizes (compared to placebo), publications with thousands of citations or in top tier journals, official recognition by the leading scientific body on pain research (IASP), and key note talks at the mainstream academic conferences on pain research.
Spontaneous healing and placebo effects happen all the time of course. But in the cases I know, it was often very unlikely to happen at the exact time of treatment. Clear improvement was often timed precisely to the day, hour or even minute of treatments. In my case, a single psychotherapy session brought me from ~25% to ~85% improvement for leg pain, in both knees at once, after it lasted for years. Similar things happened with other pains in a short amount of time after they lasted for between 4 to 30 months.
> Lastly, ignoring symptoms can be pretty dangerous so I recommend caution with the approach
I also fear that knowing about neuroplastic pain will lead certain types of people to ignore physical problems and suffer serious damage.
That’s good to know.
For what it’s worth, ME/CFS (a disease/cluster of specific symptoms) is quite different from idiopathic chronic fatigue (a single symptom). Confusing the two is one of the major issues in the literature. Many people with ME/CFS, like I, don’t even have ‘feeling tired’ as a symptom. Which is why I avoid the term CFS.