“Always close my door with the key in the lock.”
It prevents me from closing the door without having my keys on me.
“Always close my door with the key in the lock.”
It prevents me from closing the door without having my keys on me.
That’s certainly also an option. I personally found for myself, that I feel intuitively less drawn to NaCl+KCl than to NaCl + K2CO3 (I have both at home).
Most supplements that have mixes of electrolytes don’t seem to use KCl and so would give you relatively less chloride than the NaCl+KCl mix.
In addition to that from my perspective, I think that if every day of the year you consume the same amount of potassium you (as a typical office worker) likely consume either too much or too little on some days.
While I still don’t feel like I understand electrolytes as well as I would like to, I become more convinced that supplementing potassium when one engages in activities that produce sweating is worthwhile.
Over the last year I started using potassium carbonate like a spice and whether or not it feels tasty depends a lot on how much I was sweating in the day before the meal.
Giving that summer comes up, if you aren’t already supplementing electrolytes for those days that are warm enough to make you sweat, I recommend you to get some potassium carbonate and experiment with it. It’s worth noting that you need relatively tiny amounts, so if you start experimenting with it start really low as it’s easy too put too much into the food and make the food taste bad.
Supplementing sweat out electrolytes seem to reduce the feeling of being drained from the summer heat.
These days companies frequently buy back shares because they can do that without having to pay taxes for that.
It seems to me like many of those business conglomerates are privately held. The stock market seems to prefer if businesses parts that have no synergy with the main business get sold off.
On the stock market it’s easy for capital owners to diversify their assets. When companies are privately held building such business conglomerates might be the way to diversify.
Survival vs self-expression: Survival values prioritize security over liberty. Those with survival values tend to be more homophobic, uninterested in political action, distrustful of outsiders, and less happy. As people transition from industrial to knowledge societies, their sense of agency increases and they move towards self-expression values.
To me, the empiric status of that claim feels quite unclear. Is that your personal opinion? Is it a general pattern for which there’s existing data?
Most companies don’t threaten their employees with physical violence. According to another Boeing whistleblower Sam Salehpour, that seems to happen at Boeing.
Being a defense contractor, I would expect Boeing corporate to have better relationships with the kind of people you would hire for such a task than corporations.
Poisoning someone with MRSA infection seems possible but if that’s what happened it’s capabilities that are not easily available. If such a thing would happen in another case, people would likely speak about nation-state capabilities.
The cancer must develop neoantigens that are sufficiently distinct from human surface proteins and consistent across the cancer.
This is not necessarily true. There are some proteins that get produced by embryos and not by adult humans. Sometimes cancer mutates in a way that those proteins get produced by cancer cells.
While the vaccines that target a single of those embryo proteins did not do enough in clinical trials, I don’t see a reason why we should completely ignore those proteins.
Cancer cells must be isolated and have their surface proteins characterized.
Given that cancer cells engage in necrososis much more than regular cells you don’t need to isolate cancer cells to get the DNA of cancer. ctDNA can in theory be used to sequence the cancer. Using ctDNA might even be better because it gives you a better idea of whether a mutation is present in most of the cancer cells or only the section from which you removed cells.
Individualized cancer vaccines are not yet practical
Moderna has just put an individualized cancer vaccine into a phase III trial after positive results from a phase 2b trial:
Hirawat was referring to Moderna and Merck’s December announcement of positive results from a 157-patient phase 2b trial dubbed KEYNOTE-942. The pair said a combination of their personalized mRNA cancer vaccine, coded mRNA-4157 or V940, and the PD-1 inhibitor Keytruda slashed the risk of tumor recurrence or death by 44% compared with Keytruda alone when used as an adjuvant therapy in stage 3⁄4 melanoma following complete surgical resection.
Do you think that trial is a bad idea?
The question of what kind of sun exposure leads to visible skin aging is an empiric one. Saying “We err on the cautious side and assume that an arbitrary value of 0.5 SED could be regarded as an acceptable daily erythemal exposure” does not imply that there’s no visible skin aging under that arbitrary value.
The linked post suggests that your assumptions about memory are wrong:
Interestingly, I asked her for two 2-digit numbers again toward the end of that hour, having no memory that I had already done this. She told me that she had already given me two numbers, and asked whether I wanted the same numbers again. I said yes (so I could compare my performance). The second time, I was able to do the multiplication pretty quickly without needing to ask for the numbers to be repeated.
He had training effects from multiplying the two numbers despite not having a memory of the first time he multiplied them.
This is a narrow objection to the IMO hyperbolic focus on government assault risks.
Whether or not you face government assault risks depends on what you do. Most people don’t face government assault risks. Some people engage in work or activism that results in them having government assault risks.
The Chinese government has strategic goals and most people are unimportant to those. Some people however work on topics like AI policy in which the Chinese government has an interest.
Politico wrote, “Perhaps the most pressing concern is around the Chinese government’s potential access to troves of data from TikTok’s millions of users.” The concern that TikTok supposedly is spyware is frequently made in discussions about why it should be banned.
If the main issue is content moderation decisions, the best way to deal with it would be to legislate transparency around content moderation decisions and require TikTok to outsource the moderation decisions to some US contractor.
I don’t have confidence in my models of how coherent and competent governments are at getting and using data like this.
The Office of the Director of National Intelligence wrote a report about this question that was declassified last year. They use the abbreviation CAI for “commercially accessible data”.
“2.5. (U) Counter-Intelligence Risks in CAI. There is also a growing recognition that CAI, as a generally available resource, offers intelligence benefits to our adversaries, some of which may create counter-intelligence risk for the IC. For example, the January 2021 CSIS report cited above also urges the IC to “test and demonstrate the utility of OSINT and AI in analysis on critical threats, such as the adversary use of AI-enabled capabilities in disinformation and influence operations.”
Last month there was a political fight about warrant requirements when the US intelligence agencies use commercially brought data, that was likely partly caused by the concerns from that report.
I think the tension is what does it even mean to be targeted by a government.
Here, I mean that you are doing something that’s of interest to Chinese intelligence services. People who want to lobby for Chinese AI policy probably fall under that class.
I’m not sure to what extent people working at top AI labs might be blackmailed by the Chinese government to do things like give them their source code.
The FDC just fined US phone carriers for sharing the location data of US customers to anyone willing to buy them. The fines don’t seem to be high enough to deter this kind of behavior.
That likely includes either directly or indirectly the Chinese government.
What does the US Congress do to protect spying by China? Of course, banning tik tok instead of actually protecting the data of US citizens.
If you have thread models that the Chinese government might target you, assume that they know where your phone is and shut it of when going somewhere you don’t want the Chinese government (or for that matter anyone with a decent amount of capital) to know.
Isn’t the main argument that Zvi makes that China is willing to do AI regulation and thus we can also do AI regulation.
In that frame the fact that Meta releases it’s weights is just regulatory failure on our part.
Using the word ‘cruxy’ encourages people to use the mental model of what the cruxes in the conversation happen to be. Encouraging the use of effective mental models is a useful task for language.
This response appears to discourage “holistic” treatments with “no herbal products have been shown to be effective for treating cancer”, despite a large body of evidence to the contrary (like green tea reliably slowing metastasis, and garlic for slowing tumor growth by immune system support + a bunch of other pathways (GARLIC IS SO OP)).
As far as I remember “effective for treating cancer” usually means an increase in cancer survival time. Drugs that do show some slowing of tumor growth but where the patient still dies at the same time are not considered effective for treatment of cancer.
There are many poisons that you can give people that slow tumor growth but that don’t increase patient lifespan, do it makes sense to define “effective for treating cancer” that way.
Bike lanes don’t only exist to get people from point A to point B. They also exist to provide an outlet for biking as a recreational activity.
I would trust decisions based on empiric measurements of usage of the bike lanes a lot over your analysis when it comes to justifying decisions by cities.