Now, it’s still possible that accumulation of slow-turnover senescent cells could cause the increased production rate of fast-turnover senescent cells.
Reminds me of this paper, in which they replaced the blood of old rats with a neutral solution (not the blood of young rats), and found large rejuvinative effects. IIRC, they attributed it to knocking the old rats out of some sort of “senescent equilibrium”
Reminds me of this paper, in which they replaced the blood of old rats with a neutral solution (not the blood of young rats), and found large rejuvinative effects. IIRC, they attributed it to knocking the old rats out of some sort of “senescent equilibrium”
The Conboys are looking to start human trials with they neutral blood replacement approach (https://newatlas.com/medical/diluted-blood-plasma-reverse-aging-in-mice/?utm_source=New+Atlas+Subscribers&utm_campaign=9db0c9efb9-EMAIL_CAMPAIGN_2020_06_16_01_29&utm_medium=email&utm_term=0_65b67362bd-9db0c9efb9-92444869).
I didn’t realize they were tying their work to senescent cells though.