[Instrumentalism about science] has a long and rather sorry philosophical history: most contemporary philosophers of science regard it as fairly conclusively refuted. But I think it’s easier to see what’s wrong with it just by noticing that real science just isn’t like this. According to instrumentalism, palaeontologists talk about dinosaurs so they can understand fossils, astrophysicists talk about stars so they can understand photoplates, virologists talk about viruses so they can understand NMR instruments, and particle physicists talk about the Higgs Boson so they can understand the LHC. In each case, it’s quite clear that instrumentalism is the wrong way around. Science is not “about” experiments; science is about the world, and experiments are part of its toolkit.
David Wallace
This criticism of instrumentalism only works in so far as instrumentalism is descriptive, rather than prescriptive.