People who fund billion dollar trials normally demand that they be run by relatively cautious people. That conflicts with the need for innovative models.
The good news is that there’s wide variation in how expensive trials need to be. The larger the effect size, the smaller the trial can be—see the TRIIM trial.
People who fund billion dollar trials normally demand that they be run by relatively cautious people. That conflicts with the need for innovative models.
The good news is that there’s wide variation in how expensive trials need to be. The larger the effect size, the smaller the trial can be—see the TRIIM trial.