It only has any chance of working against things your immune system can attack effectively. So “fungal toxins” are probably a nonstarter, but if you’ve got fungal spores in the air and are worried about having mould grow in your lungs or something it might maybe be able to do something.
Except that if you’re already exposed to whatever-it-is, that exposure is probably more effective in training your immune system than a vaccine would be. So it would only be useful for things you’re not usually exposed to much but anticipate being exposed to in the not-too-distant future. So e.g. if you’re living in a squalid apartment with mould growing on the walls, this isn’t going to help even conditional on RadVac-style vaccines (1) working at all and (2) enabling your immune system to do something useful against the mould.
Existing approaches to toxoids like aflatoxin and ricin use specially built molecules where something immunoreactive is modified to be bonded to an antigen. A peptide vaccine that doesn’t require the chemistry would be pretty cool.
The vaccine for morphine works the same way. The immune system recognizes the opiate pharmacophore and binds to it, so that opiates don’t bind to their receptors and therefore, heroin rats don’t get high.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558830/
I’ve always wondered if it could be used for organic fungal toxins and other common airborne hazards
It only has any chance of working against things your immune system can attack effectively. So “fungal toxins” are probably a nonstarter, but if you’ve got fungal spores in the air and are worried about having mould grow in your lungs or something it might maybe be able to do something.
Except that if you’re already exposed to whatever-it-is, that exposure is probably more effective in training your immune system than a vaccine would be. So it would only be useful for things you’re not usually exposed to much but anticipate being exposed to in the not-too-distant future. So e.g. if you’re living in a squalid apartment with mould growing on the walls, this isn’t going to help even conditional on RadVac-style vaccines (1) working at all and (2) enabling your immune system to do something useful against the mould.
Thank you for educating me.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979841/
Existing approaches to toxoids like aflatoxin and ricin use specially built molecules where something immunoreactive is modified to be bonded to an antigen. A peptide vaccine that doesn’t require the chemistry would be pretty cool.
The vaccine for morphine works the same way. The immune system recognizes the opiate pharmacophore and binds to it, so that opiates don’t bind to their receptors and therefore, heroin rats don’t get high. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558830/