This isn’t even to the level of a hypothesis yet, but I think periodontal disease, which effects a great deal of people, may be significantly ameliorated by taking an NSAID like ibuprofen 20-40 minutes prior to brushing and flossing, due to the reduced gum inflammation decreasing periodontal pocket depth and allowing access to the pathogenic bacteria.
This isn’t even to the level of a hypothesis yet, but I think periodontal disease, which effects a great deal of people, may be significantly ameliorated by taking an NSAID like ibuprofen 20-40 minutes prior to brushing and flossing, due to the reduced gum inflammation decreasing periodontal pocket depth and allowing access to the pathogenic bacteria.